Treatment of labial melanotic macules on the lip. These are benign spots that appear on the lips for no apparent reason. The causes are mostly genetic, but similar spots can appear in Freckle on Lip: Meaning, Causes and Is It Dangerous? (Labial Melanotic Macule) La Bouche Parfaite Happy Wednesday! , In this video, a patients labial melanotic macule (a benign pigmented lesion) is being treated with liquid nitrogen. Labial melanotic macules are flat and asymmetrical with a ORAL MELANOTIC MACULE (OMM) (Also called focal melanosis labial melanotic macule) A benign, localized, flat pigmented lesion of the oral mucosa Caused by a focal increase in melanin production Dental Update Malignant oral melanoma: how to spot it and how it is managed Dental Update Laser Lip Treatment for Lip Discoloration: Patient Transformation