“Melanosis” in the small and large intestine Classification of HES diagnoses using ICD 10 Download Scientific Diagram ICD 10 Code for Melena K92.1 Codify by AAPC This is how laxative abuse affects colon resulting in melanosis coli . Pathology Outlines Melanosis coli Melanosis coli is dark brown black pigmentation of colorectal mucosa associated with chronic use of laxatives containing anthraquinone. Examples of such laxatives include senna and rhubarb derivatives. Clinical Importance: There is no association